hrp0089p3-p105 | Diabetes & Insulin P3 | ESPE2018

Monogenic Diabetes Cause by Mutation of the Gene HNF–1A

Narvaez Juan Manuel , Leon Maria Clemente , Oriol Josep

Introduction: The MODY diabetes (Maturity Onset Diabetes of the Young) belongs to monogenic alterations group, the mutation of the gene HNF-1α is the most common and present an autosomal dominant inheritance that causes dysfunction of the Beta pancreatic cell and alteration in the reabsorption of glucose to renal level, with age of variable presentations, it often leads to a misdiagnosis as type 1 diabetes mellitus.Description of the clinical case: ...